Ergothioneine

Item No.: Ergothioneine
Chemical Name:  Ergothioneine
CAS No.:  497-30-3
Appearance:  White Fine Powder
Molecular Fomula:  C9H15N3O2S
Description

Product Description


Ergothioneine is a natural antioxidant that can protect cells in the human body and is an important active substance in the body. Natural antioxidants are safe and non-toxic, and have become a research hotspot. As a natural antioxidant, ergothioneine has entered people's field of vision. It has various physiological functions such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal cell growth and cellular immunity. Ergothioneine is a natural molecule isolated from the fungus Ergot rye and later found in rat red blood cells, liver and many other animal tissues. Its antioxidant properties may provide compound therapeutic potential, or may be used as a food additive or cosmetic.

 

Product Name Ergothioneine
Appearance White Powder
Specification 99%
CAS 497-30-3
Package 1kg/aluminum foil bag; 25kg/drum
Sample Available
Storage Dry Place
Shelf life 2 Years

Product Function


Anti-oxidize effect

Ergothioneine is a natural amino acid that is derived from plants and can be accumulated in animals. Studies have shown that it has the effect of antioxidants. It can effectively remove -OH, chelate ferrous ions and copper ions, and prevent H2O2. Under the action of iron ions or copper ions, -OH is generated, and it can also inhibit the oxidation of copper ion-dependent oxyhemoglobin. It can also inhibit the peroxidation of arachidonic acid after the mixing of myoglobin (or hemoglobin) with H2O2. reaction. Ergothioneine also potently scavenges hypochlorous acid, thereby preventing the inactivation of a 1-antiprotease. However, it cannot inhibit the peroxidation of lipid particles in the presence of iron ions. AKanmu D et al. have shown that a certain concentration of ergothioneine can act as an antioxidant in the body.

Protective effect on cells

Ergothioneine is a powerful hypochlorous acid scavenger (HOCl), and while many compounds react with hypochlorous acid, few react as rapidly as ergothioneine. a 1-Anti-protease inhibitors (APIs), such as elastase, are particularly sensitive to hypochlorous acid, while ergothioneine at physiological concentrations is very effective in protecting APIs against inactivation by hypochlorous acid, due to the Neutrophils are the main source of hypochlorous acid in the body, and one of the effects of ergothioneine is to protect red blood cells from harm from neutrophils from normal function or from sites of diseased inflammation.

Anti-inflammatory effect

Peroxynitrite is endogenously formed by the limited diffusion reaction of NO and superoxide, and is a strong oxidant involved in the pathophysiology of inflammation, such as ischemia-reperfusion injury, atherosclerosis, acute pneumonia, and sepsis. Ergothioneine can inhibit peroxynitrite-mediated amino acid oxidation, such as tyrosine nitration, thus providing feasibility for the treatment of inflammation.

 

Product Application  


Acts as a Unique Antioxidant

Ergothioneine is a highly protective, non-toxic natural antioxidant that is not easily oxidized in water, which allows them to reach mmol concentrations in certain tissues and stimulates the cell's natural antioxidant defense system . Among the many antioxidants, ergothioneine is particularly unique, because ergothioneine can chelate heavy metal ions, which can protect red blood cells in the body from free radical damage.

Added to cosmetics as a skin protectant

Ultraviolet UVA in sunlight can penetrate into the dermis layer of human skin, affect the growth of epidermal cells, make surface cells die, and cause premature skin aging, while ultraviolet UVB is more likely to lead to the occurrence of skin cancer. Ergothioneine can minimize the formation of reactive oxygen species and protect cells from radiation damage. Therefore, ergothioneine can be added to certain cosmetics as a skin protectant for the development of outdoor skin care products and protective cosmetics.

 

More Information

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Skin whitening products are commercially available for cosmetic purposes in order to obtain a lighter skin appearance. They are also utilized for clinical treatment of pigmentary disorders such as melasma or postinflammatory hyperpigmentation.
   
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  501-30-4 Kojic Acid   331-39-5 Caffeic acid  
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  305-84-0 Carnosine   69-72-7 Salicylic Acid/BHA  
  497-30-3 Ergothioneine   - Alpha Hydroxy Acid/AHA  
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