Product Description

Ergothioneine is a natural antioxidant that can protect cells in the human body and is an important active substance in the body. Natural antioxidants are safe and non-toxic, and have become a research hotspot. As a natural antioxidant, ergothioneine has entered people's field of vision. It has various physiological functions such as scavenging free radicals, detoxification, maintaining DNA biosynthesis, normal cell growth and cellular immunity. Ergothioneine is a natural molecule isolated from the fungus Ergot rye and later found in rat red blood cells, liver and many other animal tissues. Its antioxidant properties may provide compound therapeutic potential, or may be used as a food additive or cosmetic.

 

Product Function

Anti-oxidize effect

Ergothioneine is a natural amino acid that is derived from plants and can be accumulated in animals. Studies have shown that it has the effect of antioxidants. It can effectively remove -OH, chelate ferrous ions and copper ions, and prevent H2O2. Under the action of iron ions or copper ions, -OH is generated, and it can also inhibit the oxidation of copper ion-dependent oxyhemoglobin. It can also inhibit the peroxidation of arachidonic acid after the mixing of myoglobin (or hemoglobin) with H2O2. reaction. Ergothioneine also potently scavenges hypochlorous acid, thereby preventing the inactivation of a 1-antiprotease. However, it cannot inhibit the peroxidation of lipid particles in the presence of iron ions. AKanmu D et al. have shown that a certain concentration of ergothioneine can act as an antioxidant in the body.

Protective effect on cells

Ergothioneine is a powerful hypochlorous acid scavenger (HOCl), and while many compounds react with hypochlorous acid, few react as rapidly as ergothioneine. a 1-Anti-protease inhibitors (APIs), such as elastase, are particularly sensitive to hypochlorous acid, while ergothioneine at physiological concentrations is very effective in protecting APIs against inactivation by hypochlorous acid, due to the Neutrophils are the main source of hypochlorous acid in the body, and one of the effects of ergothioneine is to protect red blood cells from harm from neutrophils from normal function or from sites of diseased inflammation.

Anti-inflammatory effect

Peroxynitrite is endogenously formed by the limited diffusion reaction of NO and superoxide, and is a strong oxidant involved in the pathophysiology of inflammation, such as ischemia-reperfusion injury, atherosclerosis, acute pneumonia, and sepsis. Ergothioneine can inhibit peroxynitrite-mediated amino acid oxidation, such as tyrosine nitration, thus providing feasibility for the treatment of inflammation.
 

Product Application  

Acts as a Unique Antioxidant

Ergothioneine is a highly protective, non-toxic natural antioxidant that is not easily oxidized in water, which allows them to reach mmol concentrations in certain tissues and stimulates the cell's natural antioxidant defense system . Among the many antioxidants, ergothioneine is particularly unique, because ergothioneine can chelate heavy metal ions, which can protect red blood cells in the body from free radical damage.

Added to cosmetics as a skin protectant

Ultraviolet UVA in sunlight can penetrate into the dermis layer of human skin, affect the growth of epidermal cells, make surface cells die, and cause premature skin aging, while ultraviolet UVB is more likely to lead to the occurrence of skin cancer. Ergothioneine can minimize the formation of reactive oxygen species and protect cells from radiation damage. Therefore, ergothioneine can be added to certain cosmetics as a skin protectant for the development of outdoor skin care products and protective cosmetics.
 

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	Cas No.	Product Name		Cas No.			Product Name
	183476-82-6	VC-IP/Ascorbyl Tetraisopalmitate		1077-28-7			A-Lipoic Acid
	84380-01-8	Alpha Arbutin		305-84-0			Carnosine
	497-76-7	Beta Arbutin		497-30-3			Ergothioneine
	53936-56-4	Deoxyarbutin		175357-18-3			Undecylenoyl Phenylalanine/Sepiwhite MSH
	501-30-4	Kojic Acid		331-39-5			Caffeic acid
	79725-98-7	Kojic Acid Dipalmitate		86404-04-8			3-o-ethyl ascorbic acid
	123-31-9	Hydroquinone		103-16-2			Monobenzone
	1105025-85-1	Dimethymethoxyl Chromanyl Palmitate		114040-31-2			Magnesium Ascorbyl Phosphate
	1197-18-8	Tranexamic Acid		66170-10-3			Sodium Ascorbyl Phosphate
	922165-31-9	Neosolue-aqulio		123-99-9			Azelaic Acid
	96702-03-3	Ectoin		84696-21-9			Hydrocotyle Asiatica Extract
	83923-51-7	Dimethylmethoxy Chromanol		90-64-2			Mandelic acid
	79-14-1	Glycolic Acid		73-31-4			Melatonin
	7402-28-0	1,4-Dipropionyloxybenzene		152312-71-5			Potassium 4-Methoxysalicylate/4-MSK
	1077-28-7	A-Lipoic Acid		129499-78-1			Ascorbyl Glucoside/AA2G
	305-84-0	Carnosine		69-72-7			Salicylic Acid/BHA
	497-30-3	Ergothioneine		-			Alpha Hydroxy Acid/AHA
	175357-18-3	Undecylenoyl Phenylalanine/Sepiwhite MSH		83-86-3			Phytic acid
	331-39-5	Caffeic acid		-			Snow White
	98-92-0	Niacinamide		-			Giga White
	90082-87-4	Plum, ext		-			Glabridin
	36062-04-1	Tetrahydrocurcumin		36062-04-1			Tetrahydrocurcuminoids
	85-27-8	Symwhite 377/Phenylethyl Resorcinol		68797-35-3			Dipotassium Glycyrrhizinate
	922165-31-9	Neosolue-aqulio		19771-63-2			Procysteine

 
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