Glutathione exists in both reduced (GSH) and oxidized (GSSG) states. In the reduced state, the thiol group of cysteine is able to donate a reducing equivalent (H++ e−) to other molecules, such as reactive oxygen species to neutralize them, or to protein cysteines to maintain their reduced forms. With donating an electron, glutathione itself becomes reactive and readily reacts with another reactive glutathione to form glutathione disulfide (GSSG). Such a reaction is probable due to the relatively high concentration of glutathione in cells (up to 7 mM in the liver).
Generally, interactions between GSH and other molecules with higher relative electrophilicity deplete GSH levels within the cell. An exception to this case involves the sensitivity of GSH to the electrophilic compound's relative concentration. In high concentrations, the organic molecule Diethyl maleate fully depleted GSH levels in cells. However, in low concentrations, a minor decrease in cellular GSH levels was followed by a two-fold increase.
Enterprise Standard Nutraceuticals Grade
1. Raw Material Glutathione Reduced role of clinical treatment and prevention
(1) To protect the liver, detoxification, inactivation of hormones, and to promote bile acid metabolism and help absorb fat and fat-soluble vitamins digestive tract.
(2) Anti-allergy, or inflammation caused by hypoxemia in patients with systemic or local, can reduce cell damage and promote repair.
(3) To improve the course of certain diseases and symptoms as adjuvant drugs. Such as: hepatitis, hemolytic disease, and keratitis, cataract and retinal diseases, such as eye disease and improve vision.
2. Food additives
(1) added to pasta, to make manufacturers reduce the time of bread to the original one-half or one third, and serve to strengthen the role of food nutrition and other features.
(2) to add to the yogurt and baby food, the equivalent of vitamin C, can play a stabilizing agent.
(3) in its mix to the surimi to prevent color deepened.
(4) to the meat and cheese and other foods, have enhanced the effect of flavor.
3. Beauty products
Prevent the infiltration of Los tyrosinase in order to achieve the purpose of inhibiting melanin formation. On eliminate wrinkles, increase skin elasticity, shrink pores, lighten pigment, the body has an excellent whitening effect. Glutathione as the main ingredient in cosmetic products in Europe and the United States was welcomed by the decades.
IDENTIFICATION .A.INFRAREDABSORPTION〈197K〉 . B.OPTICALROTATION,SpecificRotation〈781S〉Samplesolution:40 mg/mLinwater Acceptancecriteria:− 15.5。to− 17.5。, at 20。 ASSAY .PROCEDURE Sample:500 mgofglutathionepreviouslydried Titrimetricsystem (See Titrimetry〈541〉 .) Mode:Directtitration Titrant:0.1 NiodineVS Endpointdetection:Visual Blank:50 mLofmetaphosphoricacid (1 in 50)Analysis:DissolvetheSamplein 50 mLofmetaphos- phoricacid (1 in 50) andtitratewiththeTitrant. Calculate the percentageofglutathione (C10 H17 N3O6S) in theportionofGlutathionetaken: Result =[(V − B) × N × F × 100]/W V = titrantvolumeoftheSample(mL) B = titrantvolumeoftheBlank(mL) N = titrantnormality (mEq/mL) F = equivalencyfactor, 307.32 mg/mEq W = weightoftheSample(mg) Acceptancecriteria:98.0%– 101.0% onthedriedbasis IMPURITIES InorganicImpurities .AMMONIUM Standardsolution:10 µgofammoniumfromadiluted ammoniumchloridesolution Samplesolution:50 mgofGlutathione Analysis:TransfertheSamplesolutionandtheStandardsolutiontoseparate 25-mLjarsfittedwithcaps, and dissolvein 1mLofwater. Add 0.30 gofmagnesium oxide. Closeimmediatelyafterplacingapieceofsilver manganesepaper 5-mmsquare, wettedwith a few dropsofwater,underthecaps. Swirl, avoiding projectionsofliquid, andallowtostandat40。for 30 min. Acceptancecriteria:Ifthesilvermanganesepaper showsagraycolor, itisnotmoreintensethanthe standard (NMT 200 ppm). .ARSENIC〈211〉:NMT 2 ppm .CHLORIDEANDS
Learn about our shipping methods for international cosmetic ingredients, plant extract and supplements orders. Our international carriers include FedEx, UPS, and DHL Express. Choose a shipping option that best fits your budget and needs. However, in some cases we reserve the right, without notice, to change the shipping service on your order due to high value. UPS will be switched to FedEx Ground and a signature upon delivery will be required. All orders are shipped from our warehouse in China.
We ship to over 150 countries worldwide and have over 4 years of experience dealing with international shipping documentation. Please note that shipping charges may vary from the amount indicated by the automatic shipping calculator since the weight calculated on the website may differ from the actual package weight due to the packaging material. There is no handling fee for all international orders.
Customs fees, VAT, or value added tax, and sales tax are typically charged by the government of your country and must be paid by the customer once the package arrives. We cannot determine what these fees will be. We recommend that you check with your local customs office or post office for details on how these charges are assessed and applied. For customs clearance, a customs broker is usually needed who may charge you a brokerage fee. Packages may be held up in customs for a few days and will delay delivery.
FedEx International Economy: delivers in five business days to more than 220 countries for packages up to 150 pounds. Includes tracking. Extra services include broker service and customs cleared service. Please provide your FedEx account number in the "Shipping Instructions" section of your order if you want to have it shipped on your account. The prepaid shipping cost will be refunded.
FedEx International Priority: delivers in one to three business days and two business days for major cities in Europe. This shipping option is available for more than 220 countries for packages up to 150 pounds. Includes tracking. Extra services include broker service, third party consignee, and customs cleared service. Please provide your FedEx account number in the "Shipping Instructions" section of your order if you want to have it shipped on your account. The prepaid shipping cost will be refunded.
Worldwide Expedited: offers customs-cleared, day-definite delivery to more than 220 countries and territories in two to five business days.
Worldwide Express: this service offers guaranteed delivery in 1-3 business days depending on the destination. Service is available in 185 countries and territories.
Worldwide Saver: offers guaranteed afternoon delivery in 1-3 days for your international shipments. Next business day delivery to Canada, two business days to Europe and Latin America, and two or three business days to Asia. Service is available in 215 countries.
DHL Express Worldwide: DHL offers exclusively express shipping services around the globe. Slower shipping services that take longer than four to five days are not available with DHL. The Express Service is a time-sensitive service with proactive delivery notification available on request. Delivers by the end of the next possible business day. Intercontinental shipments usually take three days.
01. How to contact with us？
Online service:by Trademanager, Skype,Email
You can choose your Interested products and send inquiry to us.
Call us without any hesitation.
02. How to confirm the products quality before placing orders?
We will offer you our products specification standard to you,and we test every batch of our product by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party lab such as SGS,PONY etc.
FREE SAMPLES of some products can be sent on request,only need to pay the shipping cost or arrange a courier to us and take the samples. Send us your products specifications and requests, we will produce for you.
03. How to make order & payment?
We can accept payment by TT,WESTERN UNION,Escrow,Paypal,L/C
04. How to pack and storage?
Packing:1kg/Aluminium Floil bag with Carton outside. 25KG/Fiber drum with double PE BAGS INSIDE.
Storage:Store in cool & Dryplace,keep away from light and heat.
05. How to ship and delivery?
Transit could be DHL,UPS,TNT,FEDEX,EMS.For mass orders,it will be ship by air or sea.
06. Our reture service policy
We offer an full money back guarantee,if you are not 100% satisfied with our products,return all goods back to us within 60 days and we will fully refund your money.