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Glutathione (GSH) is named Reduced glutathione or L-GlutathioneReduced ,an important antioxidant in plants, animals, fungi, and some bacteria and archaea,a white crystalline powder. It is atripeptide with a gamma peptide linkage between the carboxyl group of the glutamate side chain and the amine group of cysteine, and the carboxyl group of cysteine is attached by normal peptide linkage to a glycine.Thiol groups are reducing agents, existing at a concentration around 5 mM in animal cells. Glutathione reduces disulfide bonds formed within cytoplasmicproteins to cysteines by serving as an electron donor. In the process, glutathione is converted to its oxidized form, glutathione disulfide (GSSG), also called L-glutathione.
INCI Name (US): | Glutathione |
INCI Name (EU): | Glutathione |
CAS #: | 70-18-8 |
General Information/ Characteristics: |
Glutathione is a skin whitener booster that is produced naturally by the liver but it’s also found in fruits, vegetables and meats. Glutathione is an antioxidant made from glycine, glutamic acid and cysteine. This compound is involved in tissue building and repairs processes, the production of proteins and chemicals needed in the body for the immune system. This antioxidant clears the body of free radicals and toxins that can lead to serious skin problems such as hyperpigmentation and melasma. Glutathione may also be beneficial for women that have cystic acne, acne-prone skin or even the occasional breakout. |
Benefits / Application: | Skin care benefits: • Functions in dermis by blocking production of melanin. • Provides skin with more natural amino acids and brightens complexion. Applications: • Rejuvenating and whitening/ lightener skin care products. |
Formulation Advice: Regulations: |
Recommended usage: 0.3 – 0.5 %. Soluble in water. pH recommended 3.0 – 5.5. No specific regulations. |
Items | Specifications | Results | |
Appearance | White or almost white, crystalline powder | White crystalline powder | |
Identification IR | Conforms to the Reference Spectrum | Conforms to the Reference Spectrum | |
Optical rotation | -15.5°to −17.5° | −16.2° | |
Appearance of solution | Not more than 200 ppm | Complied | |
Chlorides | Not more than 200 ppm | Complied | |
Sulfates | Not more than 300 ppm | Complied | |
Ammonium | Not more than 200 ppm | Complied | |
Iron | Not more than 10 ppm | Complied | |
Arsenic | Not more than 1ppm | Complied | |
Heavy metals | Not more than 10 ppm | Complied | |
Cadmium (Cd) | Not more than 1 ppm | Complied | |
Lead (Pb) | Not more than 3 ppm | Complied | |
Mercury (Hg) | Not more than 1 ppm | Complied | |
Sulfated ash | Not more than 0.1% | 0.073% | |
Loss on drying | Not more than 0.5% | 0.291% | |
Bulk density | Not less than 0.2g/ml | 0.4002g/ml | |
Tapped density | Not less than 0.4g/ml | 0.6298g/ml | |
Mesh size | Not less than 100 mesh | 100 mesh | |
Related Substances | Total | Maximum 2.0% | 1.53% |
GSSG | Maximum 1.5% | 0.44% | |
Assay | 98.0% to 101.0% | 98.6% | |
Conclusion: Complies with INN Food Grade |
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