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Oct.2022 11
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Astaxanthin - a powerful antioxidant
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Astaxanthin, also known as astaxanthin and lobster shell pigment, is a carotenoid and the highest level product of carotenoid synthesis. It is dark pink in color and its chemical structure is similar to β-carotene. β-carotene, lutein, canthaxanthin, lycopene, etc. are all intermediate products of carotenoid synthesis, so in nature, astaxanthin has the strongest antioxidant properties. Widely present in the biological world, especially in shrimp, crab, fish, algae, yeast and bird feathers, it is one of the main carotenoids in marine organisms.



  Main health benefits of astaxanthin

1 Protective effects of eye and central nervous system
The human retina and central nervous system (brain) are rich in unsaturated fatty acids, so free radicals generated by oxidation are prone to peroxidative damage. Studies have shown that astaxanthin can easily pass through the blood-brain barrier and cell membrane, can effectively prevent retinal oxidation and photoreceptor cell damage, as well as protect the central nervous system, especially the brain, so as to effectively replenish ischemia-regeneration. Perfusion injury, spinal cord injury, Parkinson's syndrome, Alzheimer's syndrome and other central nervous system injuries. In particular, the effect of macular degeneration is more significant than that of lutein.

2 Inhibits diabetic nephropathy
70% of diabetics will develop nephropathy within 5 years. Astaxanthin is the only substance found so far that can effectively prevent diabetic nephropathy. Astaxanthin is mainly by directly protecting the glomerular basement membrane and preventing the production of high blood sugar. In addition, it can also fight against the free radicals of renal tubular epithelial cells, protect the normal transport of glucose and phosphorus in renal tubular cells, thus preserve important substances such as ATP and sodium-potassium ATPase, and ensure renal blood flow. The flow is not affected and the production of proteinuria is reduced. In order to avoid the occurrence of urine bubble events, diabetic patients must start using natural astaxanthin in advance. Research has confirmed that 8 mg of astaxanthin can significantly reduce urinary protein by 70% within 8 weeks.

3 Prevention of cardiovascular disease
Clinical studies on arteriosclerosis and related cardiovascular diseases have shown that oxidation of low-density lipoprotein (LDL) is an important cause of arteriosclerosis. The higher the concentration of LDL in the human body, and the thinning of blood vessels by platelet deposition that hinders blood flow, the greater the risk of arteriosclerosis. The high-density lipoprotein (HDL) in the blood has the opposite effect, it can prevent the occurrence of arteriosclerosis. In vitro and clinical trials have shown that oral administration of 3.6 mg/d of astaxanthin per person for 2 consecutive weeks can prevent the oxidation of LDL. Unlike general LDL-lowering drugs, after taking 1.8, 3.6, 14.4 and 21.6 mg of astaxanthin daily for 2 consecutive weeks, the time of LDL oxidation was prolonged by 5.0%, 26.2%, 42.3% and 30.7%, respectively; thus preventing arterial The occurrence of atherosclerosis.

4 Protection against UV radiation
It is well known that UV radiation is an important cause of epidermal photoaging and skin cancer. Studies have shown that astaxanthin has a special effect on transglutaminase, which can consume putrescine when the skin is exposed to light. Oral astaxanthin has a stronger inhibitory effect on putrescine accumulation than oral vitamin A. Therefore, the strong antioxidant properties of astaxanthin may make it a potential photoprotectant to effectively scavenge free radicals that cause skin aging, protect cell membranes and mitochondrial membranes from oxidative damage, and be used to prevent skin photoaging.

5 Enhance immunity
Astaxanthin can significantly affect the immune function of animals. In the presence of antigens, it can significantly promote the ability of spleen cells to produce antibodies, enhance the effect of T cells, and stimulate the production of immunoglobulins in the body. Astaxanthin has a strong activity of inducing cell division and has important immunomodulatory effects.

6 Relieve exercise fatigue and enhance the body's energy metabolism
When the body moves, muscles release free radicals. If these free radicals are not dealt with in time by antioxidants, oxidative stress will occur, resulting in muscle soreness or damage to muscle tissue. Studies have shown that astaxanthin can act as an antioxidant to inhibit the oxidative damage of free radicals to the body. In addition, oral astaxanthin can also strengthen aerobic metabolism, increase muscle strength and muscle tolerance, quickly relieve exercise fatigue, and reduce delayed-onset muscle pain after strenuous exercise.

7 Anti-inflammatory and anti-infective properties
Joint pain and arthritis are often the result of oxidative damage caused by free radicals. The strong antioxidant properties of astaxanthin help inhibit free radicals and reduce their oxidative damage to joints. Studies have shown that 4mg/astaxanthin inhibits inflammatory factors (such as prostaglandin E, etc.) as effective as 4mg [cortisone], but it does not have the well-known side effects of [cortisone], so it is also known as Hormones without side effects.

8 Suppress tumors
Researchers have proposed the anticancer mechanism of astaxanthin, believing that it is related to the stability of the cell membrane and protein gene expression. It regulates intercellular communication by changing the membrane stability and the number of gene expression, thereby improving the balance between cells and maintaining the cell. normal function.




  How to distinguish the pros and cons of astaxanthin
Different sources of astaxanthin have different stereoisomers and chemical compositions. Haematococcus pluvialis is the most natural source of astaxanthin, with high safety and absorption rate; astaxanthin from fungi such as yeast, chemical synthesis, and shrimp and crab shell waste sources has low purity and safety, which is not conducive to the human body. absorb.

1 Identify accessories
Cut the rubber skin of the capsule with scissors, and drop a good astaxanthin oil into a glass of water and it will expand quickly, which is conducive to the full and rapid absorption of the gastrointestinal tract. The low-quality astaxanthin oil is a black paste when dropped into water, which cannot be dispersed and is not conducive to absorption. Capsule skins of inferior products are often opaque due to the use of artificial coloring to cover imperfections in the skin and contents.

2 recognized ingredients
If the content of astaxanthin in one astaxanthin soft capsule is 4-5 mg, then the color of one capsule in one kilogram of ordinary cooking oil is close to the color of premium salmon, because the astaxanthin of premium salmon is The nutrient content is 5 mg per kilogram.

  hint
During the use of natural astaxanthin, it is necessary to reduce or stop bad habits such as smoking, staying up late, and drinking too much, which will counteract its antioxidant effect.

Conditional can check the changes in the content of lipid metabolites such as MDA in urine to observe the effect of its use.

Because astaxanthin works by affecting and controlling oxidative damage to the cells of the organism (rather than to a specific organ), organ symptoms may not be apparent in some people. But the improvement in the lifespan of the cells was significant.

As a cosmetic, it may be better to use it externally and internally.

There are very few patients with biliary dysfunction taking fat-soluble vitamin E and astaxanthin, etc., the effect is not good, so after taking astaxanthin, be sure to check the color of the stool, if you find that the color of the stool turns red after taking astaxanthin, It means that the user has poor digestion and absorption of astaxanthin, and it is recommended to take water-soluble antioxidants such as vitamin C.



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