Glutathione, a vital tripeptide composed of glutamic acid, cysteine, and glycine, exists in two essential forms: reduced glutathione (GSH) and its derivatives, oxidized glutathione (GSSG) and acetyl glutathione (SAG). Present in nearly every human cell, as well as in various plants and animals, including wheat germ, radishes, kiwi, tomatoes, and animal livers, glutathione plays a crucial role in cellular health.
Reduced Glutathione (GSH)
GSH, commonly known as reduced glutathione, is recognized for its potent antioxidant properties. With a molecular structure containing a thiol group, GSH actively scavenges free radicals, safeguarding cells from oxidative stress. Its applications span multiple industries, including cosmetics, pharmaceuticals, and health supplements.
Oxidized Glutathione (GSSG)
Oxidized glutathione (GSSG) is the disulfide-bonded form of glutathione. Although it arises naturally within the body due to oxidative processes, an excess of GSSG can indicate cellular stress. Research suggests that the GSH/GSSG ratio is a vital biomarker for oxidative stress, making it a focus of scientific investigation.
Acetyl Glutathione (SAG)
Acetyl glutathione (SAG is a modified form of glutathione where an acetyl group is attached to the sulfur atom of cysteine. This modification enhances its stability and absorption within the body, leading to improved bioavailability. SAG is valued in the pharmaceutical and nutraceutical industries for its potential health benefits.
At Suzhou Greenway Biotech, we offer a range of glutathione products, including high-quality reduced glutathione, oxidized glutathione, and acetyl glutathione. Our products meet stringent quality standards and find applications in diverse sectors, ensuring optimal cellular health and well-being.
| Method | Raw Materials | Process | Purity | Pollution |
|---|---|---|---|---|
| Enzymatic Synthesis | L-Cysteine, L-Glutamic Acid, Glycine, Glutathione Synthetase, ATP or ADP | Fast reaction, high sensitivity, clear process, but higher cost. | High | Light |
| Solvent Extraction | Wheat Germ and Yeast | Simple and outdated process, small-scale production with low yield, low cost. | High | Light |
| Chemical Synthesis | Cysteine, Glutamic Acid, Glycine | Multiple reaction steps, time-consuming, complex operation, high cost. | Low | Heavy |
| Fermentation | Sugars | Mild reaction conditions, fast reaction, low cost. | Not high | Light |
| Reduced Glutathione (GSH) | Oxidized Glutathione (GSSG) | Acetyl Glutathione | |
|---|---|---|---|
| Status | Active | Non-active | Active |
| GSH Ratio | More than 95% | Around 1% | More than 95% |
| Function | Skincare | / | Supplement |
| Usage | Cosmetics | / | Personal Care |
| Relation | Reduced glutathione can be synthesized into oxidized glutathione. Due to the low proportion of oxidized glutathione, it has minimal physiological activity and almost no effect. Therefore, when people refer to glutathione, they usually mean reduced glutathione, and its main function is in the reduced form. S-Acetyl-L-Glutathione is the most effective variant of glutathione available in the market. Glutathione is one of the most potent antioxidants naturally produced by the human body (and the only one found inside the cells). It has been proven to neutralize free radicals, detoxify the liver, and enhance the immune system function. |
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| Product Name | L-Glutathione Reduced | Cas No. | 70-18-8 |
| Quantity | 300kg | Package | 25kg/carton |
| Storage conditions | Store in cool place(2-8℃). Keep container tightly closed in a dry and well-ventilated place. | ||
| Inspection Standard | Enterprise Standard | ||
| Items | Specifications | Results | |
| Appearance | White or almost white, crystalline powder | White crystalline powder | |
| Identification IR | Conforms to the Reference Spectrum | Conforms to the Reference Spectrum | |
| Optical rotation | -15.5°to −17.5° | −16.2° | |
| Appearance of solution | Not more than 200 ppm | Complied | |
| Chlorides | Not more than 200 ppm | Complied | |
| Sulfates | Not more than 300 ppm | Complied | |
| Ammonium | Not more than 200 ppm | Complied | |
| Iron | Not more than 10 ppm | Complied | |
| Arsenic | Not more than 1ppm | Complied | |
| Heavy metals | Not more than 10 ppm | Complied | |
| Cadmium (Cd) | Not more than 1 ppm | Complied | |
| Lead (Pb) | Not more than 3 ppm | Complied | |
| Mercury (Hg) | Not more than 1 ppm | Complied | |
| Sulfated ash | Not more than 0.1% | 0.073% | |
| Loss on drying | Not more than 0.5% | 0.291% | |
| Bulk density | Not less than 0.2g/ml | 0.4002g/ml | |
| Tapped density | Not less than 0.4g/ml | 0.6298g/ml | |
| Mesh size | Not less than 100 mesh | 100 mesh | |
| Related Substances Total GSSG |
Maximum 2.0% Maximum 1.5% |
1.53% 0.44% |
|
| Assay | 98.0% to 101.0% | 98.6% | |
| Product Name | S-Acetyl-L-Glutathione | Cas No. | 3054-47-5 | |
| Quantity | 300kgs | Packing | 25kg/Carton | |
| Item | Specification | |||
| Appearance | White or almost white, crystalline powder | |||
| Identification IR | Conforms to the Reference Spectrum | |||
| Appearance of solution | Clear and colorless | |||
| Heavy metals | Not more than 10 ppm | |||
| Ammonium | Not more than 200 ppm | |||
| Chloride | Not more than 200 ppm | |||
| Sulfate | Not more than 300 ppm | |||
| Iron | Not more than 10 ppm | |||
| Acetone | Absent | |||
| Sulfated ash | Not more than 0.2% | |||
| Loss on drying | Not more than 0.5% | |||
| Total Plate Count , cfu/g | ≤1000 | |||
| Yeast&Mold, cfu/g | ≤100 | |||
| Salmonella, cfu/g | Negative | |||
| Assay | 98.0% to 101.0% | |||
