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Product Info | Alpha Arbutin

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Update time : 2022-09-05 18:55:28
Product Name Alpha Arbutin 
English synonyms Alpha Arbutin Powder; 4-hydroquinone-alpha-d-glucopyranoside; alpha-arbutin; a-Arbutin; HydroquinoneO-alpha -D-Glucopyranoside; 4-Hydroxyphenyla-D-gChemicalbooklucopyranoside;(2R,3S,4S,5R,6S)-2-(HYDROXYMETHYL)-6-(4-HYDROXYPHENOXY)TETRAHYDROPYRAN-3,4,5-TRIOL;4-hydroxyphenylalpha-D-glucopyranoside
Molecular formula: C12H16O7
Molecular weight: 272.25
EC Number 209-795-0
                                                                                                                  
 
Melting point 195-196°C
Boiling point 561.6±50.0°C(Predicted)
Density 1.556±0.06g/cm3(Predicted)
Storage conditions 2-8°C
Solubility DMSO(Slightly),Methanol(Slightly)
Appearance Solid
Color White to Off-White
Effect α-Arbutin has a good therapeutic effect on scars caused by ultraviolet burns, and has good anti-inflammatory, repairing and whitening effects. Can inhibit the production and deposition of melanin, remove pigmentation and freckles.
Mechanism The whitening mechanism of α-arbutin directly inhibits the activity of tyrosinase, thereby reducing the production of melanin, rather than reducing the production of melanin by inhibiting cell growth or tyrosinase gene expression. Since α-arbutin is a more efficient and safer whitening active substance, many cosmetic companies at home and abroad have used α-arbutin instead of β-arbutin as a whitening additive.
Application Alpha-arbutin is a chemical, similar to arbutin, that inhibits the production and deposition of melanin, and removes pigmentation and freckles. Studies have shown that arbutin can inhibit the activity of tyrosinase at a relatively low concentration, and its inhibitory effect on tyrosinase is better than that of arbutin. Alpha-arbutin can be used in cosmetics as a whitening agent.
Purification and Identification The samples obtained by the reaction were first extracted with ethyl acetate, then extracted with n-butanol, evaporated to dryness by a rotary evaporator, and then centrifuged. The supernatant was analyzed by HPLC and compared with α-arbutin standard Compare the HPLC chromatogram of the product, compare whether the sample and α-arbutin have the same retention time of Chemicalbook, and preliminarily infer whether the sample contains α-arbutin. The product after extraction and purification was identified by the positive ion mode of LC-ESI-MS/MS. The relative molecular mass of the α-arbutin product is compared with the relative molecular weight of the α-arbutin standard to determine whether the product is α-arbutin.

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Product Info | Alpha Arbutin




 
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