Alpha-Lipoic Acid (α-LA) is a natural antioxidant with very strong antioxidant capacity, which is distributed in the liver tissue of animals and plants such as spinach and tomatoes. After α-LA is absorbed by the human body, it can be rapidly converted into dihydrolipoic acid (DHLA) in the cells and excreted outside the cells.
The combined action of α-LA and dihydrolipoic acid can remove almost all oxidative free radicals in the body, such as OH, H2O2, HClO, 1O2, OONO, NO, ROO , O2-, etc. DHLA has a low redox potential (-0.24V), it can reduce the oxidized glutathione GSSH to GSH, and can also regenerate other endogenous antioxidants such as VE, ascorbic acid and other endogenous antioxidants through redox coupling. Coenzyme Q10, etc.
Alpha-LA is a class of conditionally essential nutrients
Yellow Crystalline Powder
1kg/aluminum foil bag; 25kg/drum
Scavenge free radicals and reactive oxygen species
α-LA scavenges hydroxyl radicals ( OH), (H2O2), singlet oxygen (1O2), nitric oxide radicals (NO ), peroxynitroso ( OONO) and hypochlorous acid (HClO). Although α-LA cannot scavenge peroxide radicals (ROO ) and superoxide radicals (O-2 ), the reduced DHLA of α-LA can scavenge other radicals other than singlet oxygen. Therefore, α- LA and DHLA can scavenge all the above-mentioned free radicals in the process of mutual conversion and metabolic regeneration in vivo.
Interaction with other antioxidants
DHLA is a strong reducing agent that can reduce and regenerate many oxidative antioxidants such as ascorbic acid, vitamin E, glutathione (GSH), coenzyme Q, thioredoxin, etc. The redox of α-LA and DHLA activates the metabolic cycle of other antioxidants in the organism, forming a unique biological antioxidant regeneration cycle network, maintaining the normal level of antioxidants in the body, and jointly exerting biological antioxidant effects.
α-LA also significantly increased intracellular GSH levels. GSH is a water-soluble endogenous antioxidant involved in many important physiological processes. GSH deficiency leads to the production of reactive oxygen species and mitochondrial dysfunction, ultimately leading to neuronal apoptosis. An important biochemical feature of Parkinson's disease (PD) is a significant decrease in GSH levels, so α-LA has a positive effect on the prevention and treatment of PD. The synthesis of GSH in vivo is affected by the availability of cysteine. α-LA can be rapidly absorbed by cells and reduced to DHLA, which is dispersed into various tissues. DHLA reduces cystine to cysteine. Cysteine is absorbed by cells ten times faster than cystine, thereby accelerating GSH biosynthesis. DHLA can increase the concentration of GSH by 30% to 70%.
In the field of medicine, α-LA is widely used in the prevention and adjuvant treatment of diabetes and its related complications.
Whitening Agents Browse our wide selection active whitening ingredients
Abstract Skin whitening products are commercially available for cosmetic purposes in order to obtain a lighter skin appearance. They are also utilized for clinical treatment of pigmentary disorders such as melasma orpostinflammatory hyperpigmentation.
Whitening agents act at various levels of melanin production in the skin. Many of them are known as competitive inhibitors of tyrosinase, the key enzyme in melanogenesis.
Learn about our shipping methods for international cosmetic ingredients, plant extract and supplements orders. Our international carriers include FedEx, UPS, and DHL Express. Choose a shipping option that best fits your budget and needs. However, in some cases we reserve the right, without notice, to change the shipping service on your order due to high value. UPS will be switched to FedEx Ground and a signature upon delivery will be required. All orders are shipped from our warehouse in China.
We ship to over 150 countries worldwide and have over 4 years of experience dealing with international shipping documentation. Please note that shipping charges may vary from the amount indicated by the automatic shipping calculator since the weight calculated on the website may differ from the actual package weight due to the packaging material. There is no handling fee for all international orders.
Customs fees, VAT, or value added tax, and sales tax are typically charged by the government of your country and must be paid by the customer once the package arrives. We cannot determine what these fees will be. We recommend that you check with your local customs office or post office for details on how these charges are assessed and applied. For customs clearance, a customs broker is usually needed who may charge you a brokerage fee. Packages may be held up in customs for a few days and will delay delivery.
FedEx International Economy: delivers in five business days to more than 220 countries for packages up to 150 pounds. Includes tracking. Extra services include broker service and customs cleared service. Please provide your FedEx account number in the "Shipping Instructions" section of your order if you want to have it shipped on your account. The prepaid shipping cost will be refunded.
FedEx International Priority: delivers in one to three business days and two business days for major cities in Europe. This shipping option is available for more than 220 countries for packages up to 150 pounds. Includes tracking. Extra services include broker service, third party consignee, and customs cleared service. Please provide your FedEx account number in the "Shipping Instructions" section of your order if you want to have it shipped on your account. The prepaid shipping cost will be refunded.
Worldwide Expedited: offers customs-cleared, day-definite delivery to more than 220 countries and territories in two to five business days.
Worldwide Express: this service offers guaranteed delivery in 1-3 business days depending on the destination. Service is available in 185 countries and territories.
Worldwide Saver: offers guaranteed afternoon delivery in 1-3 days for your international shipments. Next business day delivery to Canada, two business days to Europe and Latin America, and two or three business days to Asia. Service is available in 215 countries.
DHL Express Worldwide: DHL offers exclusively express shipping services around the globe. Slower shipping services that take longer than four to five days are not available with DHL. The Express Service is a time-sensitive service with proactive delivery notification available on request. Delivers by the end of the next possible business day. Intercontinental shipments usually take three days.
01. How to contact with us？
Online service:by Trademanager, Skype,Email
You can choose your Interested products and send inquiry to us.
Call us without any hesitation.
02. How to confirm the products quality before placing orders?
We will offer you our products specification standard to you,and we test every batch of our product by HPLC.UV,GC AND TLC AND etc. We also cooperate with independent third party lab such as SGS,PONY etc.
FREE SAMPLES of some products can be sent on request,only need to pay the shipping cost or arrange a courier to us and take the samples. Send us your products specifications and requests, we will produce for you.
03. How to make order & payment?
We can accept payment by TT,WESTERN UNION,Escrow,Paypal,L/C
04. How to pack and storage?
Packing:1kg/Aluminium Floil bag with Carton outside. 25KG/Fiber drum with double PE BAGS INSIDE.
Storage:Store in cool & Dryplace,keep away from light and heat.
05. How to ship and delivery?
Transit could be DHL,UPS,TNT,FEDEX,EMS.For mass orders,it will be ship by air or sea.
06. Our reture service policy
We offer an full money back guarantee,if you are not 100% satisfied with our products,return all goods back to us within 60 days and we will fully refund your money.